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Objective To identify the diseasecausing gene of a family with upper limb predominant, slowly progressive amyotrophic lateral sclerosis (ALS), which was diagnosed as flail arm syndrome (FAS) Methods After causation of 24 known ALS genes was excluded by targeted nextgeneration sequencing, wholeexome sequencing was applied in the FAS family. H , ą'c D y K mhebert@rcbhighschoolcom y K Zmailtomhebert@rcbhighschool.
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